Analysis of the gene expression of CD4+ T lymphocytes activated with potentised sulphur from patients with periodontal inflammation and a healthy control group

Periodontitis is an inflammatory disease of the gums and periodontium that leads to tooth loss if left untreated. Every second adult suffers from a moderate form of periodontitis, every tenth adult suffers from a severe form. From an immunological point of view, certain leukocyte subpopulations are found at the site of the inflammatory reaction.

In our preliminary work on basic research projects with potentised substances in 2010 and 2015, activated CD4+ T lymphocytes and granulocytes from periodontitis blood donors have already been observed. In particular, a specific immunomodulatory effect of potentised sulphur on human cells can be assumed. Other experts in the field of basic research on homeopathy have also already taken up gene expression models. However, little is known about the gene expression of homeopathically stimulated immunomodulating human cells in a periodontitis donor group compared to a healthy control group.